CASE OF 23/F WITH VIRAL PYREXIA WITH THROMBOCYTOPENIA

This is an online e log book to discuss our patient de-identified health data shared after taking his / her / guardians signed informed consent. Here we discuss our individual patients problems through series of inputs from available global online community of experts with an aim to solve those patients clinical problem with collective current best evident based input.

This E blog also reflects my patient centered online learning portfolio and your valuable inputs on the comment box is welcome.

I have been given this case to solve in an attempt to understand the topic of  " patient clinical data analysis" to develop my competency in reading and comprehending clinical data including history, clinical findings, investigations and come up with diagnosis and treatment plan.

A 23 year old woman , who was a student
Came to the opd with chief complaints of 
1. Fever since 5 days  
2. Generalised body pains and Giddiness since 5 days 
3. Headache since 5 days 
4. Pain abdomen since 3 days 
5. Nausea and vomiting since 1 day

HOPI :
Patient was apparently asymptomatic 5 days back then she developed fever which is of high grade, intermittent associated with chills, sweating, generalised body pains and giddiness ( occasionally on getting up from bed,lasting for few seconds) .Fever relieved on taking medications. No diurnal variations and no associated rash, burning micturition,malena and loose stools 

Headache since 5 days which is diffuse, dull aching type with no aggravating and relieving factors 

Complaints of pain abdomen associated with abdominal discomfort and belching since 3 days ,increased on food intake 

Nausea and vomiting since 1 day , 2 episodes ,non bilious,non projectile,non blood stained  with food particles as content. 

For the above complaints she went to a local hospital ,where she was tested positive for dengue (NS1 Ag + ) with low platelet count (50,000 cells/cumm) and was referred to kims nkp

PAST HISTORY :
No H/O DM, HTN, asthma, TB, CAD, epilepsy 
No past surgical history 
K/c/o PCOS since 5 years and was adviced to have dietary modification
Diagnosed with Small fibroid uterus 2 years back ,took unani medication for 3 months.fibroid got resolved within 3 months
Again after 1 year , fibroid had recurred for which she continued using unani medication till now

PERSONAL HISTORY:
Consumes mixed diet 
Sleep decreased since 5 days 
Appetite reduced since 3 days 
Bowels and bladder movements regular 
No addictions 

FAMILY HISTORY : Not significant.

MENSTRUAL HISTORY:
AOM - 12 years
Before 5 Years
Regular menses,
28 days cycle,3-4 days flow
Uses 3-4 pads/day
Associated with pain and no clots

After 5 years
Irrgeular menses
Cycles irregular, 15 days of flow Sometimes 30 days flow
4/5 pads per day
Associated with clots and pain

GENERAL EXAMINATION :
Patient is conscious, coherent and cooperative 
Moderately built and moderately nourished & dehydrated
No pallor,icterus,clubbing,cyanosis,koilonychia,edema and lymphadenopathy 

VITALS :
Temp: 100 F 
PR: 84 bpm 
BP: 
Supine - 80/50 mm hg 
Standing - 90/60 mm hg 
RR: 22 cpm 
Spo2 - 95% at RA 
GRBS - 124 mg/dl 

SYSTEMIC EXAMINATION 

CARDIOVASCULAR SYSTEM:
Inspection:
Chest wall is bilaterally symmetrical.
No precordial bulge
No visible pulsations, engorged veins, scars, sinuses

Palpation:
JVP: normal
Apex beat: felt in the left 5th intercostal space in the mid clavicular line.

Auscutation:
S1, S2 heard , No murmurs

RESPIRATORY SYSTEM-
Position of trachea: central
Bilateral air entry +
Normal vesicular breath sounds - heard
No added sounds.

PER ABDOMEN:
Abdomen is soft and  tenderness present in the epigastric region .
No organomegaly.
Bowel sounds heard.
No palpable mass or free fluid 

CENTRAL NERVOUS SYSTEM:
Patient is Conscious 
Speech: normal
No signs of Meningeal irritation
Motor & sensory system: normal
Reflexes: present
Cranial nerves: intact

INVESTIGATIONS:

25/08/21 :
HEMOGRAM :
Hb:  12.5 gm/dL 
TLC:  4,500 cells/cu mm 
Neutrophils: 31 % 
Lymphocytes: 60 % 
PCV - 34.7 vol %
MCV - 81.6 fl
MCHC - 36 %
MCH - 29.4 pg
RBC: 4.25 millions/cu mm 
Platelets: 88,000 cells/cu mm 
Blood grouping - O +ve

CUE :
Albumin: nil 
Sugars: nil 
PC: 2-3 
EC: 2-3 
RBC: nil 

RFT : 
Serum creatinine: 0.6 mg/dl 
Urea - 13 mg/dl 
Uric acid - 2.8 mg/dl 
Sodium  - 140 meq/l 
K+ - 3.8 meq/l 
Cl-  102 meq/l 

RBS :119 mg/dl 
RAPID DENGUE :
NS1: Negative
IgM: Negative 
IgG: Negative 

BLOOD FOR M.P STRIP TEST  - Negative 

LFT :
Total bilirubin: 0.91 mg/dl 
Direct bilirubin: 0.20 mg/dl 
SGOT: 80 IU/l 
SGPT: 62 IU/l 
ALP: 104 IU/l 
Total protein: 5.4 gm/dl 
Albumin: 3.1 gm/dl 
A/G: 1.34 

CXR - PA VIEW

ECG

USG :
Gall bladder wall edema 
Mild ascites

26/08/21 :
HEMOGRAM 
Hb - 12.4 gm/dl
TLC:  8,100 cells/cu mm 
Neutrophils: 19 % 
Lymphocytes: 73 % 
PCV - 35.5 vol %
MCV - 82.4 fl
MCHC - 34.9 %
MCH - 28.8 pg
RBC: 4.31 millions/cu mm 
Platelets: 53,000 cells/cu mm 

27/08/21
Hb - 11.6 gm/dl
TLC:  8,100 cells/cu mm 
Neutrophils: 20 % 
Lymphocytes: 73 % 
PCV - 33.4 vol %
MCV - 82.7 fl
MCHC - 34.7 %
MCH - 28.7 pg
RBC: 4.04 millions/cu mm 
Platelets: 95,000 cells/cu mm 

28/08/2021
Hb - 11.8 gm/dl
TLC: 7,600 cells/cu mm 
Neutrophils: 32 % 
Lymphocytes: 55 % 
PCV - 34 vol %
MCV - 82.9 fl
MCHC - 34.7 %
MCH - 28.8 pg
RBC: 4.10 millions/cu mm 
Platelets: 1.0 lakhs/cu mm

29/08/21
30/08/21
FEVER CHARTING

PROVISIONAL DIAGNOSIS :
VIRAL PYREXIA
 WITH THROMBOCYTOPENIA

TREATMENT GIVEN :
1. IVF: 500 ml 1 NS, & 1 RL@100ml/hr 
2. Plenty of oral fluids
3. Inj. PAN 40 mg/IV/OD  
4. Tab. Dolo 650mg/TID. 
5. Inj. NEOMOL 1gm/IV/SOS if temp > 101 F 
6. Inj ZOFER 4mg/iv/sos 
7. Watch for bleeding manifestations  
8.Temperature monitoring 4th hourly & tepid sponging
9. Postural B.P monitoring 

DAY 1 :
SOAP NOTES
SUBJECTIVE :
Fever
Giddiness
Pain abdomen

OBJECTIVE :
Temperature - 101 F
Bp
Supine - 80/50 mm hg
Standing - 90/60 mm hg
PR - 68 bpm
SPO2 - 98% at RA
GRBS - 124 mg/dl

Platelet - 53,000 cells/cumm

ASSESSMENT :
VIRAL PYREXIA WITH THROMBOCYTOPENIA

PLAN OF CARE :
1. IVF: 500 ml 1 NS, & 1 RL@100ml/hr 
2. Inj. PAN 40 mg/IV/OD  
3. Tab. Dolo 650mg/TID. 
4. Inj. NEOMOL 1gm/IV/SOS if temp > 101 F 
5. Inj ZOFER 4mg/iv/sos 
6. Watch for bleeding manifestations  
7.Temperature monitoring 4th hourly 
8. Postural B.P monitoring

DAY 2 :
SOAP NOTES
SUBJECTIVE :
Fever spikes absent
Pain abdomen
Burning micturition

OBJECTIVE :
Temperature - 97.7 F
Bp :
Supine - 90/60 mm hg
Standing - 80/60 mm hg
PR - 72 bpm
RR - 16 cpm
SPO2 - 98% at RA
GRBS - 92 mg/dl

Platelet - 95,000 cells/cumm

ASSESSMENT :
VIRAL PYREXIA WITH THROMBOCYTOPENIA

PLAN OF CARE :
1. IVF: 500 ml 1 NS, & 1 RL@100ml/hr 
2. Inj. PAN 40 mg/IV/BD
3. Tab. Dolo 650mg/TID. 
4. Inj. NEOMOL 1gm/IV/SOS if temp > 101 F 
5. Tab BUSCOPAN 10 mg PO/TID
6. Inj ZOFER 4mg/iv/sos 
7. Syp CITRALKA 10 ml in half glass of water TID
8. Watch for bleeding manifestations  
9.Temperature monitoring 4th hourly 
10. Daily postural B.P monitoring

DAY 3 :
SOAP NOTES
SUBJECTIVE :
Fever spikes absent
Pain abdomen decreased
Burning micturition resolved

OBJECTIVE :
Temperature - Afebrile
Bp :
Supine - 100/80 mm hg
Standing - 90/70 mm hg
PR - 68 bpm
RR - 16 cpm
SPO2 - 98% at RA
GRBS - 126 mg/dl

Platelet - 1 lakh cells/cumm

ASSESSMENT :
VIRAL PYREXIA WITH THROMBOCYTOPENIA

PLAN OF CARE :
1. IVF: 500 ml 1 NS, & 1 RL@100ml/hr 
2. Inj. PAN 40 mg/IV/BD
3. Tab. Dolo 650mg/sos
4. Inj. NEOMOL 1gm/IV/SOS if temp > 101 F 
5. Tab BUSCOPAN 10 mg PO/TID
6. Inj ZOFER 4mg/iv/sos 
7. Syp CITRALKA 10 ml in half glass of water TID
8. Watch for bleeding manifestations  
9.Temperature monitoring 4th hourly 
10. Daily postural B.P monitoring

DAY 4 :
SOAP NOTES
SUBJECTIVE :
Fever spikes absent
Pain abdomen resolved
Burning micturition resolved

OBJECTIVE :
Temperature - Afebrile
Bp :
Supine - 90/80 mm hg
Standing - 90/70 mm hg
PR - 68 bpm
RR - 16 cpm
SPO2 - 98% at RA
GRBS - 126 mg/dl

Platelet - 1.6 lakh cells/cumm

ASSESSMENT :
VIRAL PYREXIA WITH THROMBOCYTOPENIA

PLAN OF CARE :
1. IVF: 500 ml 1 NS, & 1 RL@100ml/hr 
2. Inj. PAN 40 mg/IV/BD
3. Tab. Dolo 650mg/sos
4. Inj. NEOMOL 1gm/IV/SOS if temp > 101 F 
5. Tab BUSCOPAN 10 mg PO/TID
6. Inj ZOFER 4mg/iv/sos 
7. Syp CITRALKA 10 ml in half glass of water TID
8. Watch for bleeding manifestations  
9.Temperature monitoring 4th hourly 
10. Daily postural B.P monitoring

Comments

Popular Posts