CASE DISCUSSION 6 : 57 year ol man with jaundice ,pedal edema and abdominal distension


MOUNIKA KETHAVATH
ROLL NUMBER : 86

I have been given this case to solve in an attempt to understand the topic of patient clinical data analysis and to develop competency in reading & comprehending clinical data including history,clinical findings,investigations & come up with a diagnosis & treatment plan

My analysis of this case is found in the link below

https://swathibogari158.blogspot.com/2020/09/chronic-decompensated-liver-disease.html


Patient is chronic alcoholic since 40years daily 180ml of whisky taken and ocasionally toddy

Patient is non smoker,non diabetic and non hypertensive,no history of cad,cva tb, asthma

Pt is obese with gross abdominal obesity

Patient was apparently asymptomatic 3years ago then he noticed yellowish discoloration of eyes,bilateral pedal edema which is pitting type extending upto knees and abdominal distension 

Then he went to local hospital (maxcure) and got lft  done which showed mild derangement 

Then he had bleeding gums and 2 days history of bilious vomitings ,no black stools 

Patient got endoscopy done which didnt show any varices according to history (report not available)

Pedal edema decreased after medications but always mild edema and abdominal distension were present

Patient didnt stop alcohol and continued taking it everyday . One and half year later patient developed gradual increase in right lower limb swelling which is pitting type extending upto upper thigh with gross swelling and skin thickening were present , local rise of temperature present , he even had blebs (no history of trauma)which he punctured himself later it got infected so he was taken to thirumala hospital in 2018 where he was started on antibiotics ,piptaz and albumin infusions 

Debridement was done

Reports in 2018:

Tb-2.20, DB-0.70,ALP-89,SGOT-22 ,SGPT-36

HB-13.7 ,TLC-4,800,PLT -4.8 Lakhs

S.creatinine -0.9,Na -138,K-3.9,Cl-101

Usg abdomen:

Moderate hepatosplenomegaly

Cholelithiasis(largest showing 6mm)

Small right renal calculus

Liver enlarged with coarse echotexture and nodular contour

2decho:normal

But swelling and skin thickening remained same  

Endoscopy was done 3yrs ago and 1 and half year back which was normal again according to his daughter 

No history of fever, pain abdomen or vomitings were present 
Since 1 months patient was complaining of abdominal distension and shortness of breath on lying down and exertion 
Patient attenders were giving history of multiple self medications whenever patient developed fever or shortness of breath they used to take decadron injections, larigo tablets,monocef and pantop over 4 months intermittently 
Inspite of swelling and ulcerations patient used to do his regular activities and used to see opd ,no history of loss of appetite and used to ride bike and ho to hospital and going to washroom on his own 
Since 1 month patient daughter giving history of forgetfulness ,depression and fear of dying 
Since 5 days patient developed sudden increase in swelling of left lower limb with blebs,ulceration and increased temperature so he came to our hospital on Saturday and got dressing done 
Since 1 week patient was bedridden and has generalised weakness and complaints of black stools intermittently 
       23/9/2019      11/09             19/09           21/09
Hb- 12.4                     5.1                 4.8                3.6
Tlc - 4,600          8,800               9,400           10,600
Plt - 80,000          90,000           85,000          1 lakh
Esr on 11/09 - 90mm/hr

11/09 s.creat-1.2 (outside hospital)
Urea-39

LFT ON 11/09 (OUTSIDE HOSPITAL)
TB-5 , DB-2.3 ,ALP-102 ,SGOT -55 ,
SGPT -43 , Alb-4.3

19/09 (our hospital report)
TB-3.6 , DB -2.84 ,SGOT-36 ,SGPT-29
ALP-224 , ALB-1.6
19/09 :
PT -20sec 
INR -1.4
APTT-38sec
SEROLOGY NEGATIVE 

O/E : patient is conscious,coherent ,cooperative 

Obese ,pallor present

Icterus

Clubbing absent 
Cyanosis absent
Pedal Edema present 
Lymphadenopathy absent 
Ulcer on right lower limb 
Hematoma on left lower limb over shin
VITALS:
Temp afebrile
bp-100/60 mmhg ,
PR - 120bpm 
Spo2 -96% on room air ,
RR- 34 cpm
CVS -S1S2 heard no murmers 
RS-decreased air entry and bilateral fine crepitations are present in IAA,ISA,MA 
P/A- grossly distended with flat umbilicus 
Bowel sounds present

Investigations:
Hb-3.6 
Tlc-10,600
Plt- 1 lakh
TB -2.75 ,DB- 2.43,ALP-213 ,ALB-1.4
SGOT-31 ,SGPT -26
Retic count - 1
PT - 35 
INR - 2.59
APTT - more than 1 min
RFT: 
Urea - 77 , creat-1.1 ,Na-129, K -4.4 ,Cl-98
Ecg
Chestx ray
CUE
 pus cells 4-5
Albumin + 
Sugar - nil 

Treatment: 
Ecg is normal
high protein diet (2eggs / day)
1. Air or water bed 
2. Fluid restriction <1.5litres/day 
Salt restriction <2.4gms/day
3. Inj augmentin 1.2gm IV/BD
4. Inj pan 40 mg IV/OD
5. Inj zofer 4mg IV/BD
6. Tab lasilactone (20/50)mg BD 
If SBP <90mmhg -avoid 
7. Inj vit k 10mg IM/ STAT 
8. Syp lactulose 15ml/PO/BD 
9. Tab udiliv 300mg/PO/BD
10.syp hepameiz 15 ml/PO/OD
11.IVF 1 NS slowly at 30ml/hr 
12. Inj thiamine 100mg in 100mlNS /IV/TID 
13.strict BP/PR/TEMP/Spo2 CHARTING HOURLY 
14.strict I/O charting 
15.GRBS 6th hourly
16.protein x powder in glass of milk TID
17. 2FFP and 1PRBC transfusion
18 .ASD DONE
DAY2: no fresh complaints 
O/E: pt is conscious,coherent ,cooperative 
Asterixis present
Constructional apraxia
PR- 102 bpm ,low volume 
BP-100/70 mmhg ,RR-17 cpm 
Spo2-97%on RA 
CVS -S1S2 heard 
RS-bilateral AE +
P/A- distended, nontender

Investigations: 
1. Haemogram 
Hb-3.4 gm/dl
Tlc-14,000 cells/cumm
Plt -90,000cells /cumm 
2. PT -50sec
APTT- more than 1min
INR-3.7
3. S.urea-82 ,s.creat-1.5
4. Na-128 ,k -6 , cl -101 
5.usg abdomen
 

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